On Evaluation of Organ Damage in Perinatal Asphyxia: an Experimental and Clinical Study
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منابع مشابه
Association between serum interleukin-1β levels and perinatal asphyxia
Objective: Asphyxia is a major cause of acute mortality and chronic neurologic disability in neonates. We sought to define the predictive values of serum concentrations of interleukin-1β in newborns with perinatal asphyxia to see if there is a relation between interleukin-1β (IL-1β) levels to the short term neurological deficit. Methods: This was a prospective (case-co...
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The current study was conducted to correlate the level of DNA damage with multiorgan dysfunction (MOD) in perinatal asphyxia. Among the 80 cases with MOD, 25% each of the babies had five and four organ system involvement , while 23.8% of babies had involvement of 3 systems and 26.3% had 2 organ system dysfunction. The DNA damage increased with the number of systems involved. The comet tail leng...
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Using conventional criteria, a series of 26 infants was selected for intrapartum asphyxia from about 4000 deliveries over one year at a single hospital to assess the efficacy of a new biochemical method. Tissue damage was estimated from urinary excretion of hypoxanthine, an important and central intermediate in purine metabolism. The overall pattern showed agreement between the grading (by prev...
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Background: Perinatal asphyxia is a common cause of infant morbidity and mortality and long-term neurological disabilities. Due to the high costs of admission, a large proportion of births and neonatal deaths occur in non-hospital settings. This study aimed to evaluate the incidence rate of perinatal asphyxia before and after the implementation of the health improvement program. Methods: This d...
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Birth asphyxia also termed perinatal asphyxia is an obstetric complication that strongly affects brain structure and function. Central nervous system is highly susceptible to oxidative damage caused by perinatal asphyxia while activation and maturity of the proper pathways are relevant to avoiding abnormal neural development. Perinatal asphyxia is associated with high morbimortality in term and...
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